The Center for Inquiry is a daring new concept. Although modern world civilization is based upon the achievements of science and technology, until this time there has been no authoritative and credible voice defending the scientific outlook in examining religion, human values, and the borderlands of science. If the naturalistic outlook is to supplant the ancient mythological narratives of the past, it needs a new institution devoted to its articulation and dramatization to the public. The Center for Inquiry is that institution.

Their purpose is to promote and defend reason, science, and freedom of inquiry in all areas of human endeavor. They are a transnational nonpartisan, nonprofit 501(c)(3) organization that encourages evidence-based inquiry into science, pseudoscience, medicine and health, religion, ethics, secularism, and society.

Through education, research, publishing, and social services, Center for Inquiry seeks to present affirmative alternatives based on scientific naturalism. They are also interested in providing rational ethical alternatives to the reigning paranormal and religious systems of belief, and in developing communities where like-minded individuals can meet and share experiences.

This nonprofit umbrella organization oversees a diverse group of projects intended to promote science, freedom of inquiry, and secular humanist values. One of its best-known projects is "On Campus", an outreach program that helps secular students organize and operate school groups. Another program, the "Freethought Books Project", provides donations of freethought literature to prisoners and inmates in mental hospitals. The organization is also the sponsor of the annual "Women in Secularism" conference. Other activities include political lobbying, educational projects, and preservation of secular literature. The organization's headquarters is in Amherst, New York, but it also has offices in many U.S. cities as well as many countries. The website contains a press center, a store, and a forums section.